Jonathan Silva

Jonathan Silva

Professor Director of Diversity

Biomedical Engineering

  • Phone
    314-935-8837
  • Office
    Whitaker Hall, Room 290G
  • Lab location
    Whitaker Hall, Room 250 & 260

Education

PhD, Washington University in St. Louis, 2008
MS, Case Western Reserve University, 2004
BS, Johns Hopkins University, 2000

Expertise

Creating better ways to treat cardiac arrhythmia

Focus

Cardiac Arrhythmia, Molecular Imaging, Engineered Cardiomyocytes, Computational Models, Extended Reality

Research

Jonathan R. Silva applies computational and biophysical methods to improve arrhythmia therapies. Current projects include development of advanced imaging protocols to inform precision anti-arrhythmic therapies.  

Biography 

Professor Silva joined the Department of Biomedical Engineering at Washington University in St. Louis in July 2012 after receiving the Burroughs Wellcome Fund Career Award at the Scientific Interface (CASI).

Professor Silva’s laboratory has created novel algorithms that predict whether patients will respond to class I anti-arrhythmic molecules. These predictions are based on machine learning approaches that leverage a deep understanding of drug interaction biophysics. His group also developed software to provide a holographic display to physicians who perform catheter ablations for arrhythmia. This software was recently tested in humans, and the results showed that physician accuracy was significantly improved with the display. A company that he co-founded, SentiAR Inc, is commercializing the technology.

Affiliations