Research

My recent research has focused on the integration and interpretation of diverse and heterogeneous pharmacogenomics data using statistical and machine learning approaches for i) understanding driver genetics/functional (mechanism), ii) discovering novel combinatory therapies to overcome intrinsic/acquired drug resistance (with reduced toxicity and synergy effects), and iii) uncovering and perturbing the tumor-stroma interaction to understand the roles of tumor micro-environment/niche in disease development.