
Mark A. Anastasio
Professor of Electrical & Systems Engineering, Mallinckrodt Endowed Professor in Imaging Science, Vice Chair of Imaging Science & AI Research in the Mallinckrodt Institute of Radiology
Education
PhD, University of Chicago, 2001MS, University of Illinois, 1995
MSE, University of Pennsylvania, 1993
BS, Illinois Institute of Technology, 1992
Research areas
- Applications of Imaging in Science & Engineering
- Biomedical & Biological Imaging
- Cancer Imaging
- Computational Methodologies
- Computer Vision
- Image Formation and Reconstruction
- Imaging in Radiology & Radiation Therapy
- Imaging Physics
- Imaging Science in Medicine
- Machine Learning & Artificial Intelligence
- Machine Learning in Image Science
- Neuroimaging
- Quantitative Imaging
- Signals & Imaging
- Theoretical Image Science
Expertise
Develops computational and AI-enabled methods for advancing imaging science
Research
Professor Anastasio’s research broadly addresses computational and AI-enabled image science, tomographic image reconstruction and inverse problems related to image formation, and machine learning methods for clinical applications. He is an internationally recognized authority on photoacoustic computed tomography and other wave-based imaging modalities that include X-ray phase-contrast imaging and ultrasound computed tomography. Professor Anastasio is a Fellow of the Institute of Electrical and Electronics Engineers (IEEE), International Society for Optics and Photonics (SPIE), American Institute for Medical and Biological Engineering (AIMBE) and International Academy of Medical and Biological Engineering (IAMBE). He received the 2025 IEEE EMBS William J. Morlock Award for his contributions to image reconstruction and biomedical imaging technology development.Biography
Dr. Anastasio is a professor of electrical & systems engineering and the Mallinckrodt Endowed Professor in Imaging Science in the Mallinckrodt Institute of Radiology (MIR) at WashU Medicine. He also serves as the Vice Chair of Imaging Science & AI Research in the MIR, Co-Director of the Oncologic Imaging Program in the Siteman Cancer Center, and Associate Chief Research Information Officer (Biomedical Imaging) in the Institute for Informatics, Data Science & Biostatistics. He is the founding director of the Center for Computational and AI-enabled Imaging Science and co-director of the PhD Program in Imaging Science. Prior to returning to WashU, where he was previously a professor of biomedical engineering, he served as the Donald Biggar Willett Professor in Engineering and head of the Department of Bioengineering at the University of Illinois Urbana-Champaign from 2019-2025.