Mark A. Anastasio

Research

Professor Anastasio’s research broadly addresses computational and AI-enabled image science, tomographic image reconstruction and inverse problems related to image formation, and machine learning methods for clinical applications. He is an internationally recognized authority on photoacoustic computed tomography and other wave-based imaging modalities that include X-ray phase-contrast imaging and ultrasound computed tomography. 

Biography

Dr. Anastasio is a professor of electrical & systems engineering and the Mallinckrodt Endowed Professor in Imaging Science in the Mallinckrodt Institute of Radiology (MIR) at WashU Medicine. He also serves as the Vice Chair of Imaging Science & AI Research in the MIR, Co-Director of the Oncologic Imaging Program in the Siteman Cancer Center, and Associate Chief Research Information Officer (Biomedical Imaging) in the Institute for Informatics, Data Science & Biostatistics. He is the founding director of the Center for Computational and AI-enabled Imaging Science and co-director of the PhD Program in Imaging Science. Prior to returning to WashU, where he was previously a professor of biomedical engineering, he served as the Donald Biggar Willett Professor in Engineering and head of the Department of Bioengineering at the University of Illinois Urbana-Champaign from 2019-2025.

Professor Anastasio is a Fellow of the Institute of Electrical and Electronics Engineers (IEEE), International Society for Optics and Photonics (SPIE), American Institute for Medical and Biological Engineering (AIMBE) and International Academy of Medical and Biological Engineering (IAMBE). He received the 2025 IEEE EMBS William J. Morlock Award for his contributions to image reconstruction and biomedical imaging technology development.